Why we age and why we don’t have to? an army of researchers are on it!


Almost done reading Lifespan: Why we age and why we don’t have to by David Sinclair and I am pleased with what I read. This post may contain spoilers.

David Sinclair


At first glance one would look at the book cover and say it is a tall order. Not knowing who is David Sinclair, one would assume that this best selling book is another hocus self-help or motivational book. But once you start reading, you’d get to realize that this is the real thing. David has a Ph.D. in Molecular Genetics and is a researcher at Harvard Medical School. He has been working on genetic researches related to aging for many years and is well aware of the scientific advancements in that regards on almost all fronts.


The book starts with a focus on biochemistry and an outline of recent medical achievements in prolonging the lives of other living things along with researches results on human beings. The first chapters are tough to read for non medical readers but it gets better in the following chapters when David outlines his recommendations for everyone on what to do to slow down aging and potentially halt/reverse it. He goes on later in the book into addressing some societal and philosophical concerns on the effects of longer human lifespans on the way we carry on and perceive our lives.


Towards the end, he goes back to his lab at Harvard medical school, mentions many of his colleagues who are working on aging researches at different fronts. Some of whom are prominent scientists and Nobel prize winners. He lists many breakthroughs that happened in recent years and highlights the fact that all the incredible achievements he mentions in this chapter have only happened in one lab, whereas there are many of other labs, researchers and scientists working on tackling this issue all over the world.


I loved that he uses the word “army” where he says that there is an army of thousands of researchers all over the world working on understanding aging and potentially expanding healthy human lifespan to levels we have never imagined before.


The question today is not about “can we defeat aging?”, it is more about “how we do it? ” and “when will it happen?”. It is like having a million pieces jigsaw puzzle with a 100K people trying to put pieces together. We will do it, and hopefully sooner than we expect.


Loving it!

Random big thoughts


Sometimes I wish I have the time and expertise to change fields completely, study science, math and physics in depth and contribute to the human knowledge in a way or another. Unfortunately, that will remain a dream for me for the time, and maybe forever, I don’t know. But it doesn’t prevent me from reading scientific articles and wandering in thoughts of potential solutions to existential questions. And here I’d like to share with you some of them that I would explore if given the chance:

First thought:

It is big I know! and is related to our quest to send colonise Mars. And while I am not an astronomer and have little know of space beside popular science. I am wondering if there are any celestial of adequate size roaming the space between earth and Mars that we can use as stations in our future trips. We have always learnt that we have numbered planets in our solar system and that’s fine, but might it be that there are many other smaller objects orbiting the sun? objects we haven’t paid attention to and can be beneficial to us?

Can someone tell Elon Musk to explore this? It might help him achieve his dream!

Second thought:

As you know, I am very interested in the scientific advancement in biotechnology, especially those focusing in understand the ageing process and reversing it. Few months ago, a study revealed a link between gum bacteria and Alzheimer. From what I understood, it is our immune system reaction to build protective proteins shell around brain cells in order to protect it from bacteria infiltration, causing these cells to loose communication and develop the disease.

I suspect that a similar process plays a role in developing many of other age related diseases. From my read to Aubrey De Grey’s book “Ending Ageing”, I understand that the same happens to our arteries of protein accumulation over time that makes them lose their elasticity and ending in causing us strokes and heart problems. It could be like Alzheimer, an immune system reaction to protect body cells from bacteria infiltration.

I believe that Rheumatoid Arthritis is no different as well, and I think that if we focus our research in understanding the role of our microbiome in our ageing, we might be able to fix it.

Third thought:

It is about alien life! And yes, I understand the math and probability of having all those trillions planets without us detecting any form of life outside our planet. It is mind boggling and don’t make any sense. Looking at the diversity of life on our planet and the trillions of species who lived and are alive on this earth, one would wonder if that is not the case all over the universe. Having read Dan Brown’s “Origin” and the theory that states it is physical laws that predicts animate beings to pops out of inanimate objects, which very logical, then life on earth shouldn’t be that special and other celestial objects should be like microwaves with corn seeds popping life all over the space.

I think that there is something in our capabilities of seeing life on other planets. There is something that prevent us from seeing. Otherwise, life on Mars should be as diverse and common as it is here on earth.

Time will tell.

And yes my last thought is about time and space and Einstein’s theory of relativity and modern physics. I admit that I find it very difficult to understand modern physics theory and I was relieved to read the other day an article stating that maybe we are wrong trying to find a unifying theory for the universe by looking into smaller and smaller objects. And I totally agree with that. I think that we desperately need to a new model of describing the universe. We need to get out of the limitation of the time space model and think broader.

And no guys, I am not high on anything tonight!